Open Access Open Access  Restricted Access Subscription or Fee Access

Association between accelerometer-assessed physical activity and biological markers among adults with HIV

Paul D. Loprinzi, PhD, Carissa Martin, BA, Christy Kane, PhD, Jerome F. Walker, EdD


The purpose of this study was to examine the association between physical activity and CD4+ T cells and various biological markers among those with HIV. Data from the 2003- 2006 National Health and Nutrition Examination Survey were used. Participants were asked to wear an accelerometer for 7 days. A blood sample was used to detect HIV and measure various biological parameters. Nineteen adults between 18 and 48 years of age had HIV and provided sufficient accelerometry data. Physical activity was not associated with CD4+ T cells. After adjustments, moderate-to-vigorous physical activity was inversely associated with systolic blood pressure (r = −0.44), fasting glucose (r = −0.78), and waist circumference (r = −0.45). These findings suggest that HIV-infected individuals are similar to those in the general population in that that their bodies are able to adapt to the many benefits associated with physical activity.


accelerometry, biological markers, HIV, physical activity, sedentary behavior

Full Text:



Fauci AS, Pantaleo G, Stanley S, et al.: Immunopathogenic mechanisms of HIV infection. Ann Inter Med. 1996; 124(7): 654-663.

Northoff H: Exercise immunology review. Exerc Immunol Rev. 2009; 15, 5.

Morse CG, Kovacs JA: Metabolic and skeletal complications of HIV infection: The price of success. JAMA. 2006; 296(7): 844-854.

Mustafa T, Sy FS, Macera CA, et al.: Association between exercise and HIV disease progression in a cohort of homosexual men. Ann Epidemiol. 1999; 9(2): 127-131.

Bopp CM, Phillips KD, Fulk LJ, et al.: Physical activity and immunity in HIV-infected individuals. AIDS Care. 2004; 16(3): 387-393.

Ciccolo JT, Jowers EM, Bartholomew JB: The benefits of exercise training for quality of life in HIV/AIDS in the post- HAART era. Sports Med. 2004; 34(8): 487-499.

Yahiaoui A, McGough EL, Voss JG: Development of evidence-based exercise recommendations for older HIVinfected patients. J Assoc Nurses AIDS Care. 2012; 23(3): 204-219.

Chen KY, Bassett DR Jr: The technology of accelerometry- based activity monitors: Current and future. Med Sci Sports Exerc. 2005; 37(11 Suppl): S490-S500.

Troiano RP, Berrigan D, Dodd KW, et al.: Physical activity in the United States measured by accelerometer. Med Sci Sports Exerc. 2008; 40(1): 181-188.

Kronenberg F, Pereira MA, Schmitz MK, et al.: Influence of leisure time physical activity and television watching on atherosclerosis risk factors in the NHLBI Family Heart Study. Atherosclerosis. 2000; 153(2): 433-443.

Lokey EA, Tran ZV: Effects of exercise training on serum lipid and lipoprotein concentrations in women: A meta-analysis. Int J Sports Med. 1989; 10(6): 424-429.

Plaisance EP, Grandjean PW: Physical activity and high-sensitivity C-reactive protein. Sports Med. 2006; 36(5): 443-458.

Vianna MV, Ali Cader S, Gomes AL, et al.: Aerobic conditioning, blood pressure (BP) and body mass index (BMI) of older participants of the Brazilian Family Health Program (FHP) after 16 weeks of guided physical activity. Arch Gerontol Geriatr. 2012; 54(1): 210-213.

Wood N: The Health Project Book: A Handbook for New Researchers in the Field of Health. London, UK: Routledge, 2001.

Keyser RE, Peralta L, Cade WT, et al.: Functional aerobic impairment in adolescents seropositive for HIV: A quasiexperimental analysis. Arch Phys Med Rehabil. 2000; 81(11): 1479-1484.

Shephard RJ: Limits to the measurement of habitual physical activity by questionnaires. Br J Sports Med. 2003; 37(3): 197-206; discussion 206.



  • There are currently no refbacks.