Evidence supporting exercise interventions for persons in early-stage Alzheimer’s disease
DOI:
https://doi.org/10.5055/ajrt.2008.0004Keywords:
Alzheimer's, early stage, exerciseAbstract
The purpose of this article is to grade research evidence supporting exercise-based interventions for persons with early-stage dementias and to report the recommendations of a consensus panel. The search produced 11 databased articles testing the effects of exercise interventions on a variety of outcomes. The body of evidence to support exercise interventions in the prevention and treatment of Alzheimer’s disease is growing and has potential as a treatment modality following translational studies in recreation therapy and other fields.References
Hebert LE, Scherr PA, Bienjas JL, et al.: Alzheimer disease in the US population: Prevalence estimates using the 2000 census. Arch Neurol. 2003; 60(8): 1119-1122.
Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis. Arch Phys Med Rehabil. 2004; 85(10): 1694-1704.
Larson EB, Wang L, Bowen JD, et al.: Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Ann Intern Med. 2006; 144(1): 73-81.
Reisberg B, Franssen EH, Souren LE, et al.: Progression of Alzheimer’s disease: Variability and consistency: Ontogenic models, their applicability and relevance. J Neural Transm Suppl. 1998; 54, 9-20.
Adlard AP, Perreau VM, Pop V, et al.: Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer’s disease. JNeurosci. 2004; 25(17): 4217-4221.
Kramer AK, Bherer L, Colcombe SJ, et al.: Environmental influences on cognitive and brain plasticity during aging. J Gerontol. 2004; 59(9): M940-M947.
Fillit HM, Butler RN, O’Connell AW, et al.: Achieving and maintaining cognitive vitality with aging. Mayo Clinic Proc. 2002; 77(7): 681-696.
Ball LJ, Birge SJ: Prevention of brain aging and dementia. Clin Geriatric Med. 2002; 18(3): 485-503.
American College of Sports Medicine: Guidelines for Graded Exercise Testing and Exercise Prescription. Philadelphia, PA: Lea & Febiger, 1986.
Thomas VS, Hageman PA. Can neuromuscular strength and function in people with dementia be rehabilitated using resistance-exercise training? Results from a preliminary intervention study. J Gerontol A. 2003; 58(8): 746-751.
Huang CA: Tai Ji: Essential Tai Ji. Berkeley, CA: Celestial Arts of Ten Speed Press, 2001.
Teri L, Gibbons LE, McCurry SM, et al.: Exercise plus behavioral management in patients with Alzheimer disease. J Am Med Assoc. 2003; 290(15): 2015-2022.
Burgener SC, Gilbert R, Mathy R, J Alzheimer’s Dis Relat Disord, under review.
Sanglier I, Sarazin M, Zinetti, J: Tai Chi, body and cognitive rehabilitation of Alzheimer’s and related diseases. Soins. 2004; 685: 42-43.
Rosendahl E, Lindelof N, Littbrand H, et al.: High-intensity functional exercise proram and protein-enriched energy supplement for older persons dependent in activities of daily living: A randomized controlled trial. Aust JPhysiother. 2006: 52; 105-113.
Arkin SM: Student-led exercise sessions yield significant fitness gains for Alzheimer’s patients. Am J Alzheimer’s Dis Other Dement. 2003; 18(3): 159-170.
Teri L, McCurry SM, Buchner D, et al.: Exercise and activity level in Alzheimer’s disease: A potential treatment focus. J Rehabil Res and Dev. 1998; 35: 411-419.
Palleschi F, Vetta E, De Gennaro G, et al.: Effect of aerobic training on the cognitive performance of elderly patients with senile dementia of alzheimer type. Arch Gerontol Geriatr. 1996; 22: 47-50.
Rolland Y, Rival L, Pillard F, et al.: Feasibility of regular physical exercise for patients with moderate to severe Alzheimer disease. JNutr Health Aging. 2000; 4: 109-113.
Regan C, Katona C, Walker Z, et al.: Relationship of exercise and other risk factors to depression of Alzheimer disease: The LASER-AD study. Int J Geriatr Psychiatry. 2005; 20: 261-269.
Klein PJ, Adams WD: Comprehensive therapeutic benefits of Taiji: A critical review. Amer J Phys Med Rehab. 2004; 83(9): 735-745.
Khalsa DS: Integrated medicine and the prevention and reversal ofmemory loss. Altern Ther Health Med. 1998; 4(6): 38-43.
Yu F, Kolanowski A, Strumpf NE, et al.: Promoting cognition and function through exercise intervention in Alzheimer’s disease. JNurs Scholarsh. 2006; 38(4): 358-365.
Colcombe SJ, Kramer AF: Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychol Sci. 2003; 14: 125-130.
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