Polysubstance abuse associated with more frequent opioid use among patients in rural primary care settings

Authors

  • David L. Albright, PhD
  • Justin McDaniel, PhD
  • Kirsten Laha-Walsh, MSW
  • Beth Morrison, MS
  • Shanna McIntosh, MS

DOI:

https://doi.org/10.5055/jom.2020.0582

Keywords:

opioid, polysubstance, rural, SBIRT

Abstract

Objective: Opioid use is a continuing problem for the United States. Individuals who use opioids have a high risk of misuse, especially with prescription opioids. Substances that are often used in combination with opioids include methamphetamines, sedatives, and benzodiazepines, as well as tobacco, alcohol, and marijuana, but not in a medical setting. We sought to determine (a) the relationship between various drugs (eg, methamphetamine, benzodiazepines) and opioid use, as well as (b) the relationship between polysubstance use and opioid use.

Design: We created a screening instrument that requested the patients seeking medical care at Federally Qualified Health Centers (FQHC) and Veterans Affairs (VA) hospitals in West Alabama self-report their substance usage.

Setting: This study took place in outpatient primary care settings (FQHCs and VA hospitals) in west Alabama.

Participants: De-identified electronic health records for 346 adults were obtained from consenting medical facilities. Missing data were found in 33 of the records obtained. The final usable sample for this study was 311.

Main Outcome Measure: The screening tool was comprised of five sections: demographics, tobacco use, alcohol abuse, drug use, and mental health. The primary outcome measure of this study was the number of days of opioid use in the past 30 days.

Results: Thirteen individuals (4.18 percent) reported opioid use in the last 30 days. While polysubstance or dual substance use was not in the majority of the participant responses, the significant substances that were used in conjunction with opioids were methamphetamine, hallucinogens, and benzodiazepines.

Conclusions: Individuals who are polysubstance users have a higher likelihood of opioid use. Interventions that target opioid use would serve the population stronger by including screenings and potential treatments for polysubstance use additionally.

Author Biographies

David L. Albright, PhD

Hill Crest Foundation Endowed Chair, Mental Health Research, School of Social Work, University of Alabama, Tuscaloosa, Alabama

Justin McDaniel, PhD

Assistant Professor, Public Health, Southern Illinois University, Carbondale, Illinois

Kirsten Laha-Walsh, MSW

School of Social Work, University of Alabama, Tuscaloosa, Alabama

Beth Morrison, MS

Director of Wellness and Health Promotion Services, Student Health Services, Southern Illinois University, Carbondale, Illinois

Shanna McIntosh, MS

Vital Project Director, SBIRT Team, School of Social Work, Tuscaloosa, Alabama

References

National Institute on Drug Abuse: Opioid overdose crisis. Available at https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis. Accessed August 14, 2019.

Barocas JA, Wang J, Marshall BD, et al.: Sociodemographic factors and social determinants associated with toxicology confirmed polysubstance opioid-related deaths. Drug Alcohol Depend. 2019; 200: 59-63.

Seth P, Scholl L, Rudd RA, et al.: Overdose deaths involving opioids, cocaine, and psychostimulants—United States, 2015-2016. MMWR Morb Mortal Wkly Rep. 2018; 67(12): 349-358.

Scholl L, Seth P, Kariisa M, et al.: Drug and opioid-involved overdose deaths—United States, 2013-2017. MMWR Morb Mortal Wkly Rep. 2018; 67: 1419-1427.

Hadland SE, Cerda M, Li Y, et al.: Association of pharmaceutical industry marketing of opioid products to physicians with subsequent opioid prescribing. JAMA. 2018; 178(6): 861-863.

US Department of Health and Human Services: What is the US opioid epidemic. Available at https://hhs.gov/opioids-about-theepidemic/index.html. Accessed August 15, 2019.

Ghertner R: US county prevalence of retail prescription opioid sales and opioid-related hospitalizations from 2011 to 2014. Drug Alcohol Depend. 2019; 194: 330-335.

Ellis MS, Kasper ZA, Cicero TJ: Twin epidemics: The surging rise of methamphetamine use in chronic opioid users. Drug Alcohol Depend. 2018; 193: 14-20.

Winkelman TN, Chang VW, Binswanger IA: Health, polysubstance use, and criminal justice involvement among adults with varying levels of opioid use. JAMA Netw Open. 2018; 1(3): e180558.

American Addiction Centers: Dangers of mixing opiates and benzodiazepines: Vicodin, xanax, oxycodone and valium. Available at https://americanaddictioncenters.org/prescriptiondrugs/dangers-of-mixing. Accessed August 15, 2019.

Morley KI, Ferris JA, Winstock AR, et al.: Polysubstance use and misuse or abuse of prescription opioid analgesics. Pain. 2017; 158(6): 1138-1144.

Coffey W, Hunter A, Mobley E, et al.: Rural-urban trends in opioid overdose discharges in Missouri emergency departments, 2012-2016. J Rural Health. 2019; 36(2): 177-186. doi: https://doi.org/10.1111/jrh.12368.

Dunn KE, Barrett FS, Yepez-Laubach C, et al.: Opioid overdose experience, risk behaviors, and knowledge in drug users from a rural versus an urban setting. J Subst Abuse Treat. 2016; 71: 1-7.

Rigg KK, Monnat SM, Chavez MN: Opioid-related mortality in rural America: Geographic heterogeneity and intervention strategies. Int J Drug Policy. 2018; 57: 119-129.

Pear VA, Ponicki WR, Gaidus A, et al.: Urban-rural variation in the socioeconomic determinants of opioid overdose. Drug Alcohol Depend. 2019; 195: 66-73.

Monnat SM: Factors associated with county-level differences in US drug-related mortality rates. Am J Prev Med. 2018; 54(5): 611-619.

Substance Abuse and Mental Health Services Administration: Government performance and results act (GPRA) client outcome measures for discretionary programs. Available at https://spars.samhsa.gov/sites/default/files/CSATGPRATool1.pdf. Accessed August 18, 2019.

Albright DL, McDaniel JT, Kertesz S, et al.: Small area estimation and hotspot identification of opioid use disorder among military veterans living in the southern United States. Sub Abuse. 2019; 20: 1-7. doi: https://doi.org/10.1080/08897077.2019.1703066.

Centers for Disease Control and Prevention: National Center for Health Statistics: National Health Interview Survey. Available at https://www.cdc.gov/nchs/nhis/nhis_questionnaires.htm. Accessed August 18, 2019.

Saunders JB, Aasland OG, Babor TF, et al.: Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II. Addiction. 1993; 88(6): 791-804.

Kroenke K, Spitzer RL, Williams JBW: The patient health questionnaire-2. Med Care. 2003; 41(11): 1284-1292.

Tsou T-S: Robust Poisson regression. J Stat Plan Inference. 2006; 136(9): 3173-3186.

Albright DL, McDaniel JT, Kruse-Diehr AJ, et al.: Small area estimation of opioid abuse and comorbid psychological distress among females living in the thirteen Appalachian region states. Traumatology. 2019; 26(1): 61-67. doi: 10.1037/trm0000202.

Albright DL, Holmes L, Lawson M, et al.: Veteran-nonveteran differences in alcohol and drug abuse in the SBIRT program in Alabama. J Soc Work Pract Addict. 2019; 20(1): 46-58.

Gladden RM, O’Donnell J, Mattson CL, et al.: Changes in opioid-involved overdose deaths by opioid type and presence of benzodiazepines, cocaine, and methamphetamine—25 states, July-December 2017 to January-June 2018. MMWR Morb Mortal Wkly Rep. 2019; 68(34): 737-744.

Griesler PC, Hu M-C, Wall MM, et al.: Medical use and misuse of prescription opioids in the US adult population: 2016–2017. Am J Public Health. 2019; 109(9): 1258-1265.

Wu L-T, Zhu H, Swartz MS: Treatment utilization among persons with opioid use disorder in the United States. Drug Alcohol Depend. 2016; 169: 117-127.

National Institute on Drug Abuse: Opioid overdose crisis. 2019. Available at https://www.drugabuse.gov/drugs-abuse/opioids/opioid-overdose-crisis. Accessed January 15, 2020.

Published

07/01/2020

How to Cite

Albright, PhD, D. L., J. McDaniel, PhD, K. Laha-Walsh, MSW, B. Morrison, MS, and S. McIntosh, MS. “Polysubstance Abuse Associated With More Frequent Opioid Use Among Patients in Rural Primary Care Settings”. Journal of Opioid Management, vol. 16, no. 4, July 2020, pp. 283-9, doi:10.5055/jom.2020.0582.