Impact of non-benzodiazepine sleep hypnotics on opioid overdose risk

Authors

  • Van Nguyen, PharmD
  • Christopher M. Herndon, PharmD, BCACP

DOI:

https://doi.org/10.5055/jom.2020.0605

Abstract

Increasing concerns regarding concomitant use of benzodiazepines with opioids have been addressed by FDA drug safety communications and are increasingly recognized amongst prescribers. However, non-benzodiazepine sleep hypnotics continue to be prescribed with opioids.

Author Biographies

Van Nguyen, PharmD

PGY-1 Pharmacy Practice Resident, HSHS St. Elizabeth’s Hospital, O’Fallon, Illinois

Christopher M. Herndon, PharmD, BCACP

Professor, School of Pharmacy, Southern Illinois University Edwardsville, Edwardsville, Illinois

References

Cho J, Spence MM, Niu F, et al.: Risk of Overdose with Exposure to Prescription Opioids, Benzodiazepines, and Nonbenzodiazepine Sedative-Hypnotics in Adults: A Retrospective Cohort Study. J Gen Intern Med. 2020; 35: 696-703.

Turner BJ, Liang Y: Drug overdose in a retrospective cohort with non-cancer pain treated with opioids, antidepressants, and/or sedative-hypnotics: Interactions with mental health disorders. J Gen Intern Med. 2015; 30: 1081-1096.

Schifano F, Chiappini S, Corkery JM, et al.: An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions. Int J Neuropsychopharmacol. 2019; 22: 270-277.

Published

11/01/2020

How to Cite

Nguyen, PharmD, V., and C. M. Herndon, PharmD, BCACP. “Impact of Non-Benzodiazepine Sleep Hypnotics on Opioid Overdose Risk”. Journal of Opioid Management, vol. 16, no. 6, Nov. 2020, p. 400, doi:10.5055/jom.2020.0605.

Issue

Section

Letters to the Editor