Opioid prescribing patterns for distal radius fractures in the ambulatory setting: A 10-year retrospective study

Authors

DOI:

https://doi.org/10.5055/jom.0862

Keywords:

wrist fracture, quality improvement, pain management, evidence-based medicine

Abstract

Objective: Distal radius fractures (DRFs) are one of the most common orthopedic injuries, with most managed in the nonoperative ambulatory setting. The objectives of this study are to examine National Health Center Statistics (NHCS) data for DRF treated in the nonoperative ambulatory setting to identify opioid and nonopioid analgesic prescribing patterns and to determine demographic risk factors for prescription of these medications.

Design, setting, patients, and measures: This study is a retrospective analysis of data collected by the NHCS from 2007 to 2016. Utilizing International Classification of Diseases codes, all visits to emergency departments and doctors’ offices for DRFs were identified. Variables of interest included demographic data, expected payment source, and prescription of opioid or nonopioid analgesics.

Results: During the study timeframe, 15,572,531 total visits for DRFs were recorded. DRF visits requiring opioid and nonopioid analgesic prescriptions increased over time. Patients aged 45-64 years were significantly more likely to receive an opioid prescription than any other age group (p < 0.05). Opioid prescription was positively correlated with the use of workers’ compensation and negatively correlated with patients receiving services under charity care (p < 0.05).

Conclusions: Prescriptions of both opioid and nonopioid analgesic medications for DRF have been steadily increasing over time in the nonoperative ambulatory setting, with middle-aged adults most likely to receive an opioid prescription. Opioid prescription rates differ significantly between patients utilizing workers’ compensation and patients receiving services under charity care, suggesting that socioeconomic factors play a role in prescribing patterns.

Author Biographies

Brian Pettitt-Schieber, MD

Division of Plastic and Reconstructive Surgery, Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York

Robert P. Lesko, MD

Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Fei Wang, BA

Division of Plastic and Reconstructive Surgery, Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York

Jinesh Shah, MD

Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut

Joseph A. Ricci, MD

Assistant Professor, Division of Plastic and Reconstructive Surgery, Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York

References

Centers for Disease Control and Prevention: Drug overdose deaths. Available at https://www.cdc.gov/drugoverdose/deaths/index.html. Accessed December 17, 2022.

Centers for Disease Control and Prevention: Drug overdose deaths in the US up 30 percent in 2020. Available at https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2021/20210714.htm. Accessed December 17, 2022.

Webster LR: Risk factors for opioid-use disorder and overdose. Anesth Analg. 2017; 125: 1741-1748. DOI: 10.1213/ANE.0000000000002496.

Volkow ND, Jones EB, Einstein EB, et al.: Prevention and treatment of opioid misuse and addiction: A review. JAMA Psychiatry. 2019; 76: 208-216. DOI: 10.1001/jamapsychiatry.2018.3126.

Rodgers J, Cunningham K, Fitzgerald K, et al.: Opioid consumption following outpatient upper extremity surgery. J Hand Surg Am. 2012; 37: 645-650. DOI: 10.1016/j.jhsa.2012.01.035.

Labrum JT, Ilyas AM: Perioperative pain control in upper extremity surgery: Prescribing patterns, recent developments, and opioid-sparing treatment strategies. Hand (NY). 2019; 14: 439-444. DOI: 10.1177/1558944718787262.

Qin MM, Qin CD, Shah CM: Risk factors for prolonged opioid use after open treatment of distal radius fractures. Hand (NY). 2022. DOI: 10.1177/:1194-1200.

Bhashyam AR, Basilico M, Weaver MJ, et al.: Using historical variation in opioid prescribing immediately after fracture surgery to guide maximum initial prescriptions. J Orthop Trauma. 2019; 33: E131-E136. DOI: 10.1097/BOT.0000000000001392.

Butler MM, Ancona RM, Beauchamp GA, et al.: Emergency department prescription opioids as an initial exposure preceding addiction. Ann Emerg Med. 2016; 68: 202-208. DOI: 10.1016/j.annemergmed.2015.11.033.

Jeffery MM, Hooten WM, Hess EP, et al.: Opioid prescribing for opioid-naive patients in emergency departments and other settings: Characteristics of prescriptions and association with long-term use. Ann Emerg Med. 2018; 71: 326-336.e19. DOI: 10.1016/j.annemergmed.2017.08.042.

Chung KC, Spilson SV: The frequency and epidemiology of hand and forearm fractures in the United States. J Hand Surg Am. 2001; 26: 908-915. DOI: 10.1053/jhsu.2001.26322.

Nellans KW, Kowalski E, Chung KC: The epidemiology of distal radius fractures. Hand Clin. 2012; 28: 113-125. DOI: 10.1016/j.hcl.2012.02.001.

Centers for Disease Control and Prevention: Sample text for describing NHAMCS in a research article. Available at https://www.cdc.gov/nchs/data/ahcd/Sample_Text_for_Describing_NHAMCS_in_Research_Article.pdf. Accessed November 15, 2021.

Centers for Disease Control and Prevention: Datasets and documentation: Ambulatory health care data. 2020. Available at https://www.cdc.gov/nchs/ahcd/datasets_documentation_related.htm. Accessed November 15, 2021.

Shah J, Lesko RP, Lala B, et al.: Trends in opioid prescription for craniomaxillofacial trauma in the United States: An 11-year retrospective study of emergency room and office visits. Surgery. 2021; 170: 232-238. DOI: 10.1016/j.surg.2021.03.007.

Guy GP Jr, Zhang K, Bohm MK, et al.: Vital signs: Changes in opioid prescribing in the United States, 2006-2015. MMWR Morb Mortal Wkly Rep. 2017; 66: 697-704. DOI: 10.15585/mmwr.mm6626a4.

Centers for Disease Control and Prevention: Vital signs: Overdoses of prescription opioid pain relievers—United States, 1999-2010. MMWR Morb Mortal Wkly Rep. 2013; 62: 537-542.

Pletcher MJ, Kertesz SG, Kohn MA, et al.: Trends in opioid prescribing by race/ethnicity for patients seeking care in US emergency departments. JAMA. 2008; 299: 70-78. DOI: 10.1001/jama.2007.64.

Yang BK, Storr CL, Trinkoff AM, et al.: National opioid prescribing trends in emergency departments by provider type: 2005-2015. Am J Emerg Med. 2019; 37: 1439-1445. DOI: 10.1016/j.ajem.2018.10.041.

Volkow ND, McLellan TA, Cotto JH, et al.: Characteristics of opioid prescriptions in 2009. JAMA. 2011; 305: 1299-1301. DOI: 10.1001/jama.2011.401.

Naavaal S, Kelekar U: Opioid prescriptions in emergency departments: Findings from the 2016 national hospital ambulatory medical care survey. Prev Med. 2020; 136: 106035. DOI: 10.1016/j.ypmed.2020.106035.

Salzman M, Jones CW, Rafeq R, et al.: Epidemiology of opioid-related visits to US emergency departments, 1999-2013: A retrospective study from the NHAMCS (National Hospital Ambulatory Medical Care Survey). Am J Emerg Med. 2020; 38: 23-27. DOI: 10.1016/j.ajem.2019.03.052.

QuickStats: Percentage of emergency department (ED) visits for pain* at which opioids (dagger) were given or prescribed, by patient age and year—National Hospital Ambulatory Medical Care Survey, 2005-2016. MMWR Morb Mortal Wkly Rep. 2018; 67: 1400. DOI: 10.15585/mmwr.mm6750a6.

Terrell KM, Hui SL, Castelluccio P, et al.: Analgesic prescribing for patients who are discharged from an emergency department. Pain Med. 2010; 11: 1072-1077. DOI: 10.1111/j.1526-4637.2010.00884.x.

Quattromani E, Normansell D, Storkan M, et al.: Oligoanalgesia in blunt geriatric trauma. J Emerg Med. 2015; 48: 653-659. DOI: 10.1016/j.jemermed.2014.12.043.

Platts-Mills TF, Esserman DA, Brown DL, et al.: Older US emergency department patients are less likely to receive pain medication than younger patients: Results from a national survey. Ann Emerg Med. 2012; 60: 199-206. DOI: 10.1016/j.annemergmed.2011.09.014.

Platts-Mills TF, Hunold KM, Bortsov AV, et al.: More educated emergency department patients are less likely to receive opioids for acute pain. Pain. 2012; 153: 967-973. DOI: 10.1016/j.pain.2012.01.013.

Gebauer S, Salas J, Scherrer JF: Neighborhood socioeconomic status and receipt of opioid medication for new back pain diagnosis. J Am Board Fam Med. 2017; 30: 775-783. DOI: 10.3122/jabfm.2017.06.170061.

Asfaw A, Alterman T, Quay B: Prevalence and expenses of outpatient opioid prescriptions, with associated sociodemographic, economic, and work characteristics. Int J Health Serv. 2020; 50: 82-94. DOI: 10.1177/0020731419881336.

Kurani S, McCoy RG, Inselman J, et al.: Place, poverty and prescriptions: A cross-sectional study using area deprivation index to assess opioid use and drug-poisoning mortality in the USA from 2012 to 2017. BMJ Open. 2020; 10: E035376. DOI: 10.1136/bmjopen-2019-035376.

Gangavalli A, Malige A, Terres G, et al.: Misuse of opioids in orthopaedic postoperative patients. J Orthop Trauma. 2017; 31: E103-E109. DOI: 10.1097/BOT.0000000000000741.

Schoenfeld AJ, Nwosu K, Jiang W, et al.: Risk factors for prolonged opioid use following spine surgery, and the association with surgical intensity, among opioid-naive patients. J Bone Joint Surg. 2017; 99: 1247-1252. DOI: 10.2106/JBJS.16.01075.

Rhon DI, Snodgrass SJ, Cleland JA, et al.: Predictors of chronic prescription opioid use after orthopedic surgery: Derivation of a clinical prediction rule. Perioper Med. 2018; 7: 25. DOI: 10.1186/s13741-018-0105-8.

Chaudhary MA, von Keudell A, Bhulani N, et al.: Prior prescription opioid use and its influence on opioid requirements after orthopedic trauma. J Surg Res. 2019; 238: 29-34. DOI: 10.1016/j.jss.2019.01.016.

Chaudhary MA, Dalton MK, Koehlmoos TP, et al.: Identifying patterns and predictors of prescription opioid use after total joint arthroplasty. Mil Med. 2021; 186: 587-592. DOI: 10.1093/milmed/usaa573.

Dwyer CL, Soong M, Hunter A, et al.: Prospective evaluation of an opioid reduction protocol in hand surgery. J Hand Surg Am. 2018; 43: 516-522.e1. DOI: 10.1016/j.jhsa.2018.01.021.

Jamieson MD, Everhart JS, Lin JS, et al.: Reduction of opioid use after upper-extremity surgery through a predictive pain calculator and comprehensive pain plan. J Hand Surg Am. 2019; 44: 1050-1059.e4. DOI: 10.1016/j.jhsa.2019.10.002.

Stepan JG, Sacks HA, Verret CI, et al.: Standardized perioperative patient education decreases opioid use after hand surgery: A randomized controlled trial. Plast Reconstr Surg. 2021; 147: 409-418. DOI: 10.1097/PRS.0000000000007574.

Stepan JG, Sacks HA, Lovecchio FC, et al.: Opioid prescriber education and guidelines for ambulatory upper-extremity surgery: Evaluation of an institutional protocol. J Hand Surg Am. 2019; 44: 129-136. DOI: 10.1016/j.jhsa.2018.06.014.

Pflug EM, Huang S, Haquebord JH, et al.: Opioid prescribing patterns among orthopedic hand surgeons after implementation of a divisional protocol. J Healthc Qual. 2022; 44: E31-E37. DOI: 10.1097/JHQ.0000000000000330.

Published

04/01/2024

How to Cite

Pettitt-Schieber, B., R. P. Lesko, F. Wang, J. Shah, and J. A. Ricci. “Opioid Prescribing Patterns for Distal Radius Fractures in the Ambulatory Setting: A 10-Year Retrospective Study”. Journal of Opioid Management, vol. 20, no. 2, Apr. 2024, pp. 109-17, doi:10.5055/jom.0862.