The close interaction between medications used for pain management and thyroid function

Shailendra Kapoor, MD

doi:10.5055/jom.2012.0125

Authors

Shailendra Kapoor, MD

DOI:

https://doi.org/10.5055/jom.2012.0125

Keywords:

pain management, thyroid function

Abstract

No abstract

Author Biography

Shailendra Kapoor, MD

Private practice, Mechanicsville, Virginia

References

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Freire-Garabal M, Balboa JL, Nunez MJ, et al.: Autoradiographic evidence of opioid binding sites in the thyroid gland. Horm Metab Res. 1992; 24: 494-495.

Berglund LA, Millard WJ, Gabriel SM, et al.: Opiate-thyroid hormone interactions in the regulation of thyrotropin secretion in the rat. Neuroendocrinology. 1990; 52: 303-308.

Edmondson EA, Bonnet KA, Friedhoff AJ: The effect of hyperthyroidism on opiate receptor binding and pain sensitivity. Life Sci. 1990; 47: 2283-2289.

Deb I, Das S: Thyroid hormones protect astrocytes from morphine- induced apoptosis by regulating nitric oxide and pERK 1/2 pathways. Neurochem Int. 2011; 58: 861-871.

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Pfab R, Hirtl C, Zilker T: Opiate detoxification under anesthesia: No apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure. J Toxicol Clin Toxicol. 1999; 37: 43-50.