Opioid withdrawal-induced hypomania: A case series

Navid Khalili, MD; Shahrokh Sardarpour Gudarzi, MD

doi:10.5055/jom.2012.0099

Authors

Navid Khalili, MD
Shahrokh Sardarpour Gudarzi, MD

DOI:

https://doi.org/10.5055/jom.2012.0099

Keywords:

opioid, opium, hypomania, withdrawal, detoxification

Abstract

The aim of this study was to report hypomanic symptoms after opioid withdrawal. In this case series, nine opioid-dependent patients with hypomanic profile on opioid withdrawal were selected from outpatients in a private psychiatric clinic. Opium dependency was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition). Substance history, clinical features, temperament, and family history were retrospectively probed. Patients displayed pure or mixed hypomanic symptoms on opioid withdrawal. In nearly all subjects, the symptoms continued until individuals started taking the opioid again. Features of hyperthymic temperament and family history of bipolarity were traced in most of the individuals.

Author Biographies

Navid Khalili, MD

Psychiatrist, Member/Researcher of Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Shahrokh Sardarpour Gudarzi, MD

Assistant Professor, Department of Psychiatry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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