

Effect of preoperative rectal indomethacin on postoperative pain reduction after open appendectomy
Abstract
Methods: It is a simple randomized, clinical trial including 200 patients with acute appendicitis who were divided into two groups (A1 and A2). The case group (A1) received 100 mg rectal indomethacin during 2 hours before the operation. Pain intensity was assessed in all patients using a visual analog scale (VAS). Similarly, total dosage of meperidine analgesic medication and postoperative time to use of rescue analgesia were evaluated.
Results: Patients who received preoperative rectal indomethacin (A1) showed a significant reduction in the VAS score. Also, a reduction in total dose of meperidine and longer time to use of rescue analgesic medication were observed in A1 group.
Conclusion: Preoperative administration of rectal indomethacin in acute appendicitis reduces postoperative pain.
Keywords
References
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DOI: https://doi.org/10.5055/jom.2010.0006
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